Multivariate analysis of genomic variables, effective population size, and mutation rate
نویسندگان
چکیده
منابع مشابه
A phylogenetic estimator of effective population size or mutation rate.
A new estimator of the essential parameter theta = 4Ne mu from DNA polymorphism data is developed under the neutral Wright-Fisher model without recombination and population subdivision, where Ne is the effective population size and mu is the mutation rate per locus per generation. The new estimator has a variance only slightly larger than the minimum variance of all possible unbiased estimators...
متن کاملEstimating effective population size or mutation rate with microsatellites.
Microsatellites are short tandem repeats that are widely dispersed among eukaryotic genomes. Many of them are highly polymorphic; they have been used widely in genetic studies. Statistical properties of all measures of genetic variation at microsatellites critically depend upon the composite parameter theta = 4Nmicro, where N is the effective population size and micro is mutation rate per locus...
متن کاملText S 11 : Population size and mutation rate
Text S11: Population size and mutation rate Daniel J. van der Post1,2,3,∗, Rineke Verbrugge, Charlotte K. Hemelrijk 1 Institute of Artificial Intelligence, University of Groningen, P. O. Box 407, 9700 AK, Groningen, The Netherlands 2 Behavioural Ecology and Self-Organization, University of Groningen, P. O. Box 11103, 9700 CC Groningen, The Netherlands 3 Centre for Social Learning and Cognitive ...
متن کاملCritical Mutation Rate Has an Exponential Dependence on Population Size
Populations of individuals exist in a wide range of sizes, from billions of microorganisms to fewer than ten individuals in some critically endangered species saved on the brink of extinction. In any evolutionary system, there is significant evolutionary pressure to evolve sequences that are both fit and robust; at high mutation rates, individuals with greater mutational robustness can outcompe...
متن کاملEffective population size
What is it? An aid to calculation in population genetics, introduced by Sewall Wright. The rate of change of the genetic make-up of a population by genetic drift — fluctuations in allele frequencies caused by random sampling — is inversely related to the effective population size, Ne. Ne is measured with reference to an ideal ‘Wright–Fisher’ population. This has a fixed number of N diploid bree...
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ژورنال
عنوان ژورنال: BMC Research Notes
سال: 2019
ISSN: 1756-0500
DOI: 10.1186/s13104-019-4097-3